Clinical Outcomes of Presbyopia-Correcting Intraocular Lens

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María T Iradier,1 Verónica Cruz,1 Naty Gentile,1 Priscila Cedano,1 David P Piñero2

1Iradier Eye Clinic, Madrid, Spain; 2Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain

Correspondence: David P Piñero
Department of Optics, Pharmacology and Anatomy, University of Alicante, Crta San Vicente del Raspeig s/n, San Vicente del Raspeig (Alicante), 03690, Spain
Email [email protected]

Purpose: To evaluate the clinical outcomes of cataract surgery with implantation of a novel model of extended depth of focus (EDOF) intraocular lens (IOL).
Methods: Pilot case series enrolling a total of 27 eyes of 16 patients (49 to 84 years) undergoing uncomplicated phacoemulsification cataract surgery with implantation of the EDOF IOL Synthesis PLUS (Cutting Edge, Montpellier, France). Near (UNVA, uncorrected near visual acuity; DCNVA, distance-corrected near visual acuity) and distance visual acuity (uncorrected and corrected distance visual acuity, UDVA and CDVA), monocular defocus curve and refractive outcomes were evaluated during a 3-month follow-up.
Results: Mean postoperative UDVA, UNVA and DCNVA were 0.11± 0.17, 0.14± 0.22 and 0.37± 0.36 logMAR, respectively. A total of 84.6%, 91.7%, and 96.3% of eyes achieved postoperative UDVA, UNVA and CDVA of 0.20 logMAR or better. A total of 78.6% of eyes achieved postoperative DCNVA of 0.30 logMAR or better. Mean postoperative spherical equivalent was − 0.76± 0.53 D. The distance-corrected visual acuity was maintained on average over a value of 0.30 logMAR for the range of defocus levels between +1.00 and − 1.50 D.
Conclusion: The implantation of the Synthesis plus EDOF IOL after cataract surgery seems to provide functional levels of distance, intermediate and near visual acuity. The near visual performance with this new IOL might be significantly enhanced using a micro-monovision approach. The results of this pilot study should be confirmed in future clinical trials.

Keywords: presbyopia, cataract surgery, presbyopia-correcting IOL, extended depth of focus IOL, defocus curve

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